Evaluation of two different biomarkers for use in the assessment of toxic chemical exposure in California sea lions (Zalophus californianus).
نویسندگان
چکیده
a Department of Epidemiology, The University of Texas, M.D. Anderson Cancer Center, 1155 Pressler Street #1340, Houston, TX 77030, United States b Department of Preventive Medicine and Community Health, The University of Texas Medical Branch, Galveston, TX 77555, United States c Departments of Pathology and Preventive Medicine and Community Health, The University of Texas Medical Branch, Galveston, TX 77555, United States d The Marine Mammal Center, Sausalito, CA, United States
منابع مشابه
The role of organochlorines in cancer-associated mortality in California sea lions (Zalophus californianus).
Wild California sea lions (Zalophus californianus) have an unusually high prevalence of neoplasms (18% of stranded dead adults) and high levels of contaminants. The contribution of organochlorine (OC) tissue burdens to the probability of sea lions dying from carcinoma was explored using a logistic regression model. Levels of PCBs and DDTs were determined in blubber of sea lions diagnosed with m...
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Major histocompatibility complex (MHC) class II DRB genotypes were examined in two geographically isolated populations of California sea lions (Zalophus californianus) (Gulf of California and California coastal Pacific Ocean). Genomic DNA from 227 California sea lions was examined using eight sequence-specific primer (SSP) pairs flanking the putative peptide-binding site. A total of 40 differen...
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متن کاملProteomic Analysis of Plasma from California Sea Lions (Zalophus californianus) Reveals Apolipoprotein E as a Candidate Biomarker of Chronic Domoic Acid Toxicosis
Domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus) is caused by exposure to the marine biotoxin domoic acid and has been linked to massive stranding events and mortality. Diagnosis is based on clinical signs in addition to the presence of domoic acid in body fluids. Chronic DAT further is characterized by reoccurring seizures progressing to status epilepticus. Diagnosi...
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عنوان ژورنال:
- Marine pollution bulletin
دوره 52 1 شماره
صفحات -
تاریخ انتشار 2006